Egg donation is used in cases where the ovaries do not produce their own eggs (with disfunction, malformations, premature depletion of ovarian function, menopause), and in cases of repeated unsuccessful attempts of in vitro fertilization in poor quality embryos. Egg donation is also used in the case of risk of hereditary diseases.
Who can be a donor?
According to the recommendations of ASRM (Amerіcan Socіety of Reproductіve Medіcіne) and ESHE (European Socіety of Human Reproductіon and Embryology), a donor must be under 35 years have good physical and mental health. We do not use donors who have a history of cancer, heart, kidney diseases, hereditary diseases and sexually transmitted diseases, mental illness, alcoholism, drug usage.
The program of the egg donation is anonymous. A family which uses donor’s eggs cannot see donor’s photos, but only can be informed about such characteristics as: height, weight, color of hair and eyes, nationality, education, presence of family and children, blood type, and Rh factor.
Desired age of the recipient (female, for whom the donor eggs are used) is up to 50. Any information about the recipient is not available for the donor. Female recipient must be examined by the therapist and receive a conclusion from the therapist of the absence of contraindications for pregnancy and childbirth.
The efficiency of embryo transfer in patients with donor eggs slightly exceeds the efficiency in patients with conventional IVF program, reaching 50-60% per cycle.
Indications for in-vitro using donor eggs
- The absence of eggs due to natural menopause, premature ovarian failure syndrome, as after removal of the uterus, radiotherapy or chemotherapy, abnormalities of development (Turner’s syndrome, gonadal dysgenesis, etc.);
- Presence of a gene with a mutation in the egg in women with hereditary diseases, coupled with sex (Duchenne muscular dystrophy, X-linked ichthyosis, etc.);
- Unsuccessful retries in vitro in low ovarian response to hormonal stimulation, repeated delivery of poor quality embryos, the transfer of which does not lead to contraindications – such as during the procedure of in vitro.
The obligatory examinations for an egg donor:
- Blood type, Rh rhesus.
- Evaluation by a psychiatrist (once).
- Gynecological examination (before each attempt of IVF).
- Fluorography(valid 1 year).
- Blood test for HIV, RW, presence of markers of hepatitis B and C (valid3 months).
- Detection of IgG and M totoxoplasma, rubella, cytomegalovirus, herpes virus (valid 12 months).
- Smear for the degree of purity (valid 3 months).
- Bacteriological test of material from a cervical canal for chlamydia, mycoplasma, ureaplasma, trichomonas,candida, gonorrhea (valid 12 months).
- Smear on oncocytology of uterine cervix.
- Molecular genetic testing on a carriage of mucoviscidosis.
- DNA-diagnosis of Fragile X syndrome (Martin-Bell syndrome).
- DNA-diagnosis of Hoffmann’s muscular atrophy.